What is Sucrose Acetate Isobutyrate (E444)? Uses, Safe and Side Effects

What is Sucrose Acetate Isobutyrate (E444)? Uses, Safe and Side Effects


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Sucrose Acetate Isobutyrate (abbreviated as SAB) is white to faint yellow crystalline powder. SAB is a viscous saccharide ester which is considered as synthetic food ingredient. Grown in tropical climates, it has become a replacement for the natural sweetener called honey. Interested in knowing more about Sucrose Acetate Isobutyrate (E444)? Visit our blog today to learn more about this safe food additive.

What is sucrose acetate isobutyrate?

Sucrose acetate isobutyrate (also known as CAB, SAC) is a combination of two ingredients: sucrose and acetylated monoglyceride. It’s a clear liquid with no odor or taste. When added to a product, it absorbs water and becomes sticky.

Sucrose acetate isobutyrate helps keep products moist when they are exposed to air or moisture so they don’t dry out easily. It also helps with texture and consistency in gels, lotions and creams.

Sucrose acetate isobutyrate keto

Sucrose acetate isobutyrate keto (SAIBK) is a mixture of three compounds: acetylated sugars, butyric acid, and water. It’s used as a flavoring agent in foods like chewing gum, candy, baked goods and beverages.

SAIBK is produced by combining sucrose and acetylated glucose in an esterification reaction with butyric acid. The resulting product contains 60-70% sucrose (sugar), 25-35% acetylated glucose and 7-15% butyric acid.

Sucrose acetate isobutyrate glycemic index

Sucrose acetate isobutyrate (SAIB) is a sugar-based compound used as a food additive. It has been approved for use in the US by the FDA since 1997, and it’s often found in chewing gums, candies, baked goods and other foods. The glycemic index of this compound hasn’t been studied directly, but it’s likely to be very similar to that of other sugar alcohols like sorbitol and mannitol. These compounds have GI values between 13 and 20.

Sucrose acetate isobutyrate solubility

The solubility of sucrose acetate isobutyrate (SAIB) in water at 25°C is 0.42 g/L.

The solubility of SAIB in 10% ethanol was found to be 0.73 g/L at 25°C. The maximum solubility was observed at pH 4 and increased with increasing temperature from 25 to 50 °C.

Sucrose acetate isobutyrate calories

The number of calories in sucrose acetate isobutyrate depends on how much of it you consume and what type of food it’s added to:

0 grams per 1 teaspoon (5 milliliters) — Ice cream made with sucrose acetate isobutyrate contains no calories because it only has trace amounts of this sweetener added to it.

How is sucrose acetate isobutyrate made?

Chemically, sucrose acetate isobutyrate is a synthetic compound that’s used as a preservative in cosmetics and personal care products. It’s also used as a food additive in Japan, where it’s known as E967.

Sucrose acetate isobutyrate is made by reacting sucrose with acetic anhydride to yield an ester called ethyl 2-acetyloxy-3-carbamoylpropanoate. This product is then reacted with butyric acid (i.e., butyric acid chloride) to produce the final product.

Why natural flavour, carbonated water and sucrose acetate isobutyrate are in fanta pineapple?

The ingredients used in Fanta Pineapple are natural flavour, carbonated water and sucrose acetate isobutyrate.

The use of these ingredients is mainly to give the drink its distinct flavour.

Natural flavour is a combination of different flavours that can be derived from several sources such as fruits, vegetables or animal products. The natural flavour used in this drink is derived from pineapple juice.

Carbonated water is used to add fizziness to the drink while also providing a refreshing taste when you drink it. The carbonation process involves adding CO2 gas into water at high pressure which causes small bubbles to form in the liquid. Once you open the bottle of Fanta Pineapple, the CO2 escapes from the liquid which causes it to go flat over time if left unopened for too long.

Sucrose acetate isobutyrate (E 1520) is an ester formed between sucrose and acetic acid that has been approved for use as an artificial sweetener by Health Canada since 1998 (Health Canada).

What is sucrose acetate isobutyrate used for?

Sucrose acetate isobutyrate (SAIB) is a food additive used as a sweetener and humectant in foods, beverages and pharmaceuticals. It is also used in cosmetic products.

SAIB is produced by combining sugar and acetylation with butyric acid. The resulting product is then mixed with water to make a liquid that can be added to food or cosmetics.


Sucrose acetate isobutyrate (SAIB) is a cellulose ester widely used in food, beverages and cosmetics. It can be used as an emulsifier, stabilizer and thickener. SAIB is also widely used in the production of chewing gum, fruit jellies, chocolate, ice cream and other sweet foods.


Sucrose acetate isobutyrate (SAIB) is an emulsifier used in beverages such as wine, beer and carbonated soft drinks to give them a creamy texture. It also helps preserve their flavor and color.


Cosmetic applications include lotions, moisturizers and hair products to prevent dryness and brittle hair.


SAIB is a non-ionic surfactant which is used as an excipient in many pharmaceutical products. It is used in combination with other excipients and drugs to help with stability and absorption of the active ingredient.

SAIB has been shown to improve lipophilicity and solubility of poorly water soluble compounds such as peptides, proteins and vitamins. It also provides a protective layer around the active ingredient which enables it to resist degradation at high temperatures during manufacture or storage conditions.


Other Names
  • Sucrose diacetate hexaisobutyrate
  • Isobutyric acid, hexaester with sucrose diacetate
CAS Number 126-13-6
Chemical formula C40H62O19
Molecular Weight 832-856


It is a pale straw-coloured viscous liquid.


It is insoluble in water and soluble in most organic solvents.

Is sucrose acetate isobutyrate safe?

There is evidence that its safety as a food additive has been approved by the United States. The FDA, the European Food Safety Authority (EFSA), and the Joint FAO/WHO Expert Committee on Food Additives (JECFA).


In nonalcoholic beverages, SAIB may be safely used to stabilize emulsions of flavoring oils without exceeding 300 mg/kg.


Acetate isobutyrate (E444) is listed in Commission Regulation (EU) No 231/2012 as an authorised food additive and is classified as an “additives other than colours and sweeteners.”

Safety re-evaluation in 2016

Based on its study of genotoxicity, carcinogenicity, reproductive and developmental toxicity, the EFSA concluded in 2016 that sucrose acetate isobutyrate would not be a safety concern at the permitted uses and levels.

Authorised uses and levels

Among the foods that may contain it and whose maximum levels are 300 mg/kg are:

UK Food Standards Agency

In the “Others” category

Food Standards Australia New Zealand

Its code number 444 indicates that it is an approved ingredient in Australia and New Zealand.


Function Class: food additives, density adjusting agent and cloud-producing agent.

Acceptable daily intake: In 1996, an ADI of 20mg/kg was set.

Sucrose acetate isobutyrate (SAIB) is a type of sugar that can be found in a variety of lip balms, body moisturizers, and other cosmetics. It’s also used as a medicine to treat constipation in young children.

SAIB is made by combining sucrose (table sugar) with acetic acid (the main ingredient in vinegar) and adding butyric acid or another fatty acid to prevent it from crystallizing. It’s a waxy substance that dissolves easily in water and has no flavor or odor.

The Food and Drug Administration (FDA) approved SAIB for use as a food additive in 1967 after concluding that it was safe for human consumption at levels up to 2%. It’s also approved as an excipient (a substance added to a drug or cosmetic to help make it more effective or easier to use).

What are the possible side effects of sucrose acetate isobutyrate?

Sucrose acetate isobutyrate (SIAB) is a synthetic ingredient that’s used in a variety of cosmetics and personal care products, including lipsticks, foundations, lotions and sunscreens. It’s considered non-toxic and safe for use on the skin. However, it may cause temporary irritation if you have sensitive skin or allergies.

Sucrose acetate isobutyrate side effects include:

  • Skin irritation and redness or swelling of your lips
  • Itching or burning sensation on your lips
  • Nasal stuffiness or sneezing
  • Hives (itchy, raised bumps)

Is sucrose acetate isobutyrate bad for you?

Sucrose acetate isobutyrate is a common food ingredient used as a thickener, humectant, and emulsifier in food and cosmetics. It is often found in candy, chewing gum, toothpaste, mouthwash, lip balm, and other personal care products. It is also used in some vitamin supplements and nutritional supplements.

SAIB can be used in many types of foods because it doesn’t have an odor or taste. It’s often used in combination with other food additives such as xanthan gum or carrageenan to improve texture or mouth feel.

This additive has been known to cause allergic reactions in some people who are sensitive to it. Some reactions include itching and swelling around the lips, mouth and throat; hives; nausea; vomiting; dizziness; fainting; difficulty breathing; rapid heart rate; loss of consciousness; seizures; coma and death (rare).

Sucrose acetate isobutyrate cancer

There are no studies that show sucrose acetate isobutyrate causes cancer in humans or animals. However, there may be risks from consuming this ingredient at high doses over long periods of time. This would occur if you consume large amounts of foods or drinks that contain it every day for years.
Sucrose acetate isobutyrate diabetes

There are no studies showing that sucrose acetate isobutyrate causes diabetes or has any effects on blood sugar levels (such as causing low blood sugar).

Where to buy sucrose acetate isobutyrate?

You can purchase sucrose acetate isobutyrate from various online retailers such as Amazon, Walmart, or eBay. We recommend purchasing this product from Amazon because they have free shipping on orders over $49 and they also offer competitive prices on most items sold through their website.

Frequently asked questions

Is sucrose acetate isobutyrate natural?

No, sucrose acetate isobutyrate (SAIB) is a synthetic ingredient that’s used as a solvent in several types of cosmetic products, including lipstick and foundation makeup. It’s also used as an emulsifier in foods like chocolate syrup, ice cream, and candy.

Is sucrose acetate isobutyrate vegan?

Yes, sucrose acetate isobutyrate is vegan.

The ingredient is made from sucrose (sugar) and acetic acid (vinegar). The vinegar reacts with the sucrose to form the product which is then purified by distillation so that it’s clear without any impurities or solids left behind. There are no animal products involved in making this product so it’s considered vegan friendly!

Is sucrose acetate isobutyrate halal?

Yes. Sucrose acetate isobutyrate is a chemical compound that is used as a flavor and fragrance enhancer in many different food products. It is a synthetic chemical, meaning that it was created in a lab rather than naturally occurring, but it does not contain any pork products, making it suitable for consumption by Muslims who follow halal dietary restrictions.

Is sucrose acetate isobutyrate kosher?

Yes, sucrose acetate isobutyrate is kosher.

Sucrose acetate isobutyrate is a flavor enhancer that occurs naturally in many foods and beverages. It has a sweet taste, but it also has a bitter aftertaste, which means it can be used to mask unpleasant flavors and add sweetness to foods without adding calories or sugar. The kosher certification of sucrose acetate isobutyrate means that the product was not made by Jews or any other people who practice Judaism and it was produced without violating any rules of kashrut (kosher).

Is sucrose acetate isobutyrate gluten free?

Yes, sucrose acetate isobutyrate is gluten free.

According to the FDA, ingredients such as sucrose acetate isobutyrate that are derived from natural sources and do not contain any protein are considered gluten free.

Is sucrose acetate isobutyrate sugar?

No, sucrose acetate isobutyrate is a non-caloric sweetener. It is commonly used in toothpaste and chewing gum.

Is sucrose acetate isobutyrate an artificial sweetener?

No, sucrose acetate isobutyrate is not an artificial sweetener. It’s a naturally occurring compound that has been used as a food additive since the 1960s and has a long history of being used in many different types of products without any evidence of harmful effects on humans.

Is sucrose acetate isobutyrate an artificial sweetener?

No, sucrose acetate isobutyrate is not a form of artificial sweetener.

Sucrose acetate isobutyrate is an emulsifier that is used in some foods, such as dairy products and baked goods, to prevent separation of water and fat. It helps keep ingredients like butterfat and milk solids in suspension or disperse throughout the product. It can also be used in pharmaceuticals to help deliver drugs through the skin.

Is sucrose acetate isobutyrate raise insulin levels?

No, sucrose acetate isobutyrate does not raise insulin levels.

Sucrose acetate isobutyrate (SEA) is one of the most common food additives in soft drinks, but it does not raise insulin levels. It is a sweetener that is added to foods because it has a high level of sweetness and does not have any calories or carbohydrates. The FDA has approved SEA for use as an ingredient in food products.


You may now have a better understanding of what is Sucrose Acetate Isobutyrate. This chemical compound is commonly used in ice cream as a way to help extend its creamy consistency, so you’re likely ingesting small amounts of it with every bite you take. For this reason, questions have been raised about its safety, and whether or not consuming it may lead to negative health effects. And while some studies have shown that consuming high doses can lead to tumors in the thyroid and liver, but there is no clear evidence that it’s harmful to humans. Until more studies are done, you should be careful to avoid overloading on this type of sugar—but on the whole, your health shouldn’t be affected by moderate consumption of E444.

Sophie Feng

Sophie Feng

Sophie Feng is the author of gradechemical.com, she is the co-founder of the grade chemical network. She has been in grade chemical company since 2017, with a working knowledge of food chemical .

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