What is Disodium Succinate E364ii? Uses, Safety, Side Effects

What is Disodium Succinate E364ii? Uses, Safety, Side Effects


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Disodium succinate E364(ii), also called 2-succinic acid, Sodium succinate (anhydrous) is a sodium salt that is the disodium salt of succinic acid, which is a mixture of two compounds: alpha-ketoglutarate and succinic. It appears as colorless crystals or white powder. ( 1)

It is often used in meat products, snack foods, and beverages because of its unique properties that provide specific taste and texture to formulated food items. What is disodium succinate in food? What are its uses, safe and side effects? Read on so you will find out!

What is disodium succinate?

Disodium succinate is an organic compound with the chemical formula CH3CH(ONO)2. It is a white, crystalline solid that dissolves in water to give a slightly acidic solution. The salt is used as an emulsifier and thickener in foods and cosmetics, and as a preservative in pharmaceuticals.

Disodium succinate (DS) is commonly used as an emulsifier, stabilizer, and thickener in food products such as salad dressings, condiments, sauces, and frozen desserts. It can also be used as a spray-dried leavening agent for baked goods. It is also used to maintain moisture content in packaged foods by preventing water evaporation from the surface of foods during storage. DS has been shown to increase shelf life of many different types of food products. Disodium succinate is also commonly used as a preservative in pharmaceuticals because it inhibits bacterial growth at low concentrations.

What is disodium succinate used for?

Disodium succinate is a food additive used as a preservative, emulsifier and stabilizer. It is also used in cosmetics and personal care products such as shampoo, body lotion, eye shadow and face powder.

Disodium succinate food

Disodium succinate is a food additive used as a flavoring agent in meat products, gravies, soups, and sauces. It is also used as a preservative for dried foods, like potato chips and snack foods.

Disodium succinate is an additive that has been used in many foods for years. It can be found in bread, cakes, and other baked goods. Disodium succinate is also used in some mouthwashes, toothpastes, and throat lozenges to help make them more effective at reducing bad breath or killing germs in the mouth.

Disodium succinate is used in many types of food products because it helps improve the flavor of various foods while also helping to preserve them longer than they might otherwise last. Disodium succinate works by preventing bacteria from growing on food surfaces or inside of food items by inhibiting their growth.

Foods that contain it include:

  • Seasoning
  • Vinegar
  • Sauce
  • Instant noodles
  • Ham & Sausage
  • Canned seafood (fish, shellfish, cuttlefish)

Disodium succinate skincare

Disodium succinate is also used as an emulsifier and stabilizer in cosmetics and personal care products such as shampoo, body lotion, eye shadow, and face powder.

Disodium succinate hexahydrate

Disodium succinate is a chemical compound with the formula Na2C6H10O4S3. It is an important chelating agent, frequently used to sequester ions of divalent metals, especially calcium and magnesium. It is also used as a food additive, e.g., as an emulsifier and acidity regulator in cheese products and as an antioxidant in bread.

Disodium succinate hexahydrate is a crystalline substance that has many applications in the dairy industry. It is used as an emulsifier to stabilize milk fat globules, which allows them to be dispersed evenly throughout the milk liquid. This helps prevent milk from separating into cream and skim milk. Disodium succinate also helps maintain the pH of milk at about 6.3-6.4, which prevents bacterial growth and rancidity. Disodium succinate can be purchased from suppliers such as Sigma Aldrich or Fluka Chemical Corporation.

Disodium succinate hydrate is also used in baked goods such as pizza crusts and bread. The reason why disodium succinate hydrate is added to these foods is that it acts as an antioxidant by helping prevent.

Disodium tetrapropenyl succinate

Disodium tetrapropenyl succinate is a food additive, also known as E450. It is used as a flavor enhancer and preservative in foods such as baked goods, breakfast cereals, dairy products, frozen desserts and processed meats.

Disodium tetrapropenyl succinate is a synthetic ingredient created by linking together two molecules of propylene glycol with one molecule of succinic acid. When added to foods, it can help prevent them from spoiling too quickly.

Propylene glycol is a chemical used in many household products including antifreeze and latex paint. It can be toxic if ingested at high doses or over time.

Disodium tetrapropenyl succinate was approved for use in Europe in 1973, but was not approved for use in the US until 2011 when it received approval from the Food and Drug Administration (FDA).

Natural Source

Disodium succinate is a type of food additive that is used in a variety of different products, including potato chips and other snacks. It is also used as a preservative in some foods. The most common ingredient in this chemical compound is disodium succinate sodium salt.

Disodium succinate sodium salt is naturally derived from cornstarch, and it can also be made from sugar cane or beet molasses. This chemical is typically used to extend the shelf life of processed foods, as well as to help prevent them from spoiling prematurely. This preservative can also help prevent mold growth on foods that may have been exposed to moisture during storage or shipping.

Two Types

Disodium succinate is a white crystalline powder which dissolves easily in water. It is used as a food additive, as an acidity regulator, and as an emulsifier.

Disodium succinate can be made in two different forms: disodium succinate anhydrous and disodium succinate hexahydrate.

1. Disodium Succinate Anhydrous: It is also known as disodium 2-carboxyethylene-1,2-dicarboxylate dihydrate. It is made by reacting ethylene carbonate with sodium hydroxide solution and then heating it until it crystallizes out of solution. This form of disodium succinate has a melting point of around 100°C (212°F).

2. Disodium Succinate Hexahydrate: It is also known as disodium 2-carboxyethylene-1,2-dicarboxylate dihydrate heptahydrate or disodium 2-carboxyethylene-1,2-dicarboxylate dihydrate tetrahydrate or sodium hydrogen succinate anhydrous or sodium hydrogen dibasic ester of glycolic acid.

How is disodium succinate made?

Disodium succinate is a white, crystalline powder that is soluble in water and has a molecular weight of 200.24 g/mol. It is used as a food additive and pharmaceutical excipient.

Disodium succinate is produced by the reaction of succinic acid with sodium hydroxide in an autoclave.

The process involves the following steps ( 2):

  1. Succinic acid is mixed with water in a reactor vessel.
  2. Sodium hydroxide solution is added to the reactor vessel under stirring conditions. The mixture is heated, allowing for the reaction of sodium hydroxide with succinic acid to take place at elevated temperatures (80-90 ˚C).

What is disodium succinate made of?

Disodium succinate is an organic compound that is made up of two molecules of succinic acid and one molecule of sodium.

Succinic acid is a natural preservative that is produced by the human body during the Krebs cycle, which is a series of chemical reactions that take place in the mitochondria of cells.

Disodium succinate can also be found in small amounts in certain foods such as mushrooms, peanuts, canned peaches and canned tomatoes.

Disodium succinate is often used as a food additive. It serves as a flavor enhancer and preservative, helping to prevent spoiling or mold growth on foods.



An odorless, crystalline powder or granule with a special shellfish flavor.

Other Names

  • Sodium succinate hexahydrate
  • Sodium succinate
  • Butanedioic acid, disodium salt
  • Disodium butanoate
  • Succinic acid, disodium salt
  • Sodium succinate dibasic

Chemical formula and molecular weight

  • Anhydrous: C4H4Na2O4, 162.06
  • Hexahydrate: C4H4Na2O4·6H2O, 270.15





At 65 °C, it is soluble in water at 35g/100ml, but not in ethanol.


A weak diprotic acid, succinic acid has two PKas, PKa1 4.2 and PKa2 5.6.

Difference between sodium succinate and disodium succinate

Sodium succinate is a white, crystalline powder with a molecular formula of C4H6NaO4. It is produced from sucrose or glucose by reacting with sodium hydroxide in the presence of an acid catalyst.

Sodium succinate is used as an ingredient in many food products such as baked goods and breakfast cereals, as well as in cosmetics and personal care products.

Disodium succinate is also known as disodium succinate dihydrate. It has a molecular formula of C4H6Na2O8•2H2O and a molar mass of 380.58 g/mol. Disodium succinate is prepared by heating sodium carbonate to 120°C under pressure at a rate of 0.1 MPa/s until no more CO2 is evolved; then, the product is cooled to 40°C before being filtered off and dried at 80°C for 1 hour to remove moisture content below 1%.

Disodium succinate vs MSG

MSG is a natural amino acid that is commonly added to Chinese food, and it gives the food a savory taste. The problem with MSG is that it can cause adverse reactions like headaches, nausea, and vomiting.

MSG is also known as monosodium glutamate and sodium glutamate. MSG is used in processed foods as a flavor enhancer or to make the food taste more like meat. For example, MSG has been added to chicken noodle soup since the 1920s.

Disodium succinate is a byproduct of sugar production. It’s used as an emulsifier in foods such as canned vegetables, frozen vegetables and salad dressings. Disodium succinate raises blood sugar levels more slowly than sugar but it still raises blood sugar levels.

Is disodium succinate safe to eat?

Disodium succinate is regulated by the Food and Drug Administration (FDA) as a generally recognized as safe (GRAS) substance. The FDA has approved disodium succinate as an indirect food additive under 21 CFR 172.846 (a)(3). Disodium succinate can also be used in conjunction with other additives that are not GRAS listed if it does not exceed 0.5% of the finished product by weight (21 CFR 172.858).

What are the benefits of disodium succinate?

Disodium succinate is an organic compound that is used as a food additive to give a savory taste. It is also used in the production of cosmetics, detergents and pharmaceuticals.

Disodium succinate (DS) occurs naturally in fruits and vegetables. It has been identified as a non-carcinogenic compound that may be beneficial for human health.

DS has many benefits:

  • It enhances the flavor of some foods, including meat and poultry.
  • It can help with weight loss by increasing satiety.
  • It can help lower blood pressure.
  • In addition, disodium succinate can also reduce risk factors for heart disease such as high cholesterol.

What are the side effects of disodium succinate?

Disodium succinate is a food additive that is used as a flavor enhancer and preservative. The additive is found in a wide range of foods, including baked goods, meats and dairy products.

Disodium succinate is also used in some beverages and chewing gum to add flavor. The U.S. Food and Drug Administration (FDA) has approved disodium succinate as a food additive, but not all countries allow the use of this chemical in foods.

The FDA regulates the amount of disodium succinate that can be added to processed foods, but does not regulate its use in natural foods or beverages. Manufacturers are responsible for ensuring that their products do not exceed recommended levels for this chemical.

Side effects of disodium succinate may include:

  • Nausea and vomiting.
  • Heartburn.
  • Diarrhea.
  • Stomach pain.
  • Headache.
  • Dizziness.
  • Skin rash or itching.

Does disodium phosphate cause cancer?

Disodium phosphate is a salt that is used in many foods, including breads and frozen dinners. It also has many other uses in the food industry.

Disodium phosphate is generally recognized as safe (GRAS) by the Food and Drug Administration (FDA). The FDA issued this designation after reviewing studies that showed that this substance was safe for human consumption when used at levels permitted by the FDA.

The National Toxicology Program (NTP) has determined that disodium phosphate does not cause cancer or reproductive problems in rats or mice.

Where to buy disodium succinate?

Disodium succinate can be purchased from online stores such as Amazon, eBay and Aliexpress. You can also purchase it at your local store if you live in a place where it is sold. For example, if you live in the United States, you can find it at your local grocery store or supermarket.

Frequently asked questions

Is disodium succinate natural?

Yes, disodium succinate is a natural ingredient that is used in many foods and personal care products. It is made by the fermentation of sugar, starch, or glucose.

Is disodium succinate halal?

Yes, disodium succinate is a food additive that is used as a preservative and to keep the color of food from fading. It is made from the fermentation of glucose and sucrose, which are both halal.

Is disodium succinate vegan?

Yes, disodium succinate is vegan. Disodium succinate is a sodium salt of succinic acid, a byproduct of the fermentation process used to make cornstarch. It is found in many foods and drinks, including Worcestershire sauce and soy sauce.

Disodium succinate is not an animal-derived ingredient. It is not made from animal products or byproducts. As such, it does not contain any animal byproducts and is therefore suitable for vegans.

Is disodium succinate kosher?

Yes, disodium succinate is kosher. In order for a product to be considered kosher, it must be produced under rabbinic supervision and meet certain standards of quality. Disodium succinate is manufactured by the company BASF, which has been producing kosher products since the 1950s. This means that BASF produces disodium succinate using only ingredients that have been certified as kosher, and that all employees involved with production are Jewish.

Disodium succinate is sometimes used in baking as a leavening agent, but it can also be used as a stabilizer in foods like frozen desserts and candies.

Is disodium succinate gluten free?

Yes, disodium succinate is gluten free.

Disodium succinate is a salt of succinic acid, which is a naturally-occurring substance found in many foods. There are no known allergens in disodium succinate, and it does not contain any wheat or other gluten-containing ingredients.


It is still important to know what the effect of disodium succinate on your body as there are some side effects when you consume too much of this ingredient. With this, you can also pay attention to the amount that you eat especially if you are going to consume these for a long time.

Some of these has been considered as an additive in products that people consume it often in the form of dishwashing detergent and even in food coloring, so the effect may be different on different people. Because of this, it is good to know both its nutritional values and side effects so that you will be able to make a judgment whether or not it will be safe for consumption.

Sophie Feng

Sophie Feng

Sophie Feng is the author of gradechemical.com, she is the co-founder of the grade chemical network. She has been in grade chemical company since 2017, with a working knowledge of food chemical .

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