What is Dipotassium Phosphate (E340ii)? Uses, Safe, Side Effects

What is Dipotassium Phosphate (E340ii)? Uses, Safe, Side Effects


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Dipotassium Phosphate (E340ii) is a food additive that is commonly used as a leavening agent and pH control agent in products such as flour, cake mixes, and some soft drinks. It is similar to Sodium Pyrophosphate in the sense that it helps these products raise faster. However, sodium pyrophosphate is much more often used. This is due to the large amounts of potassium present in this food additive. ( 1)

It’s typically used in chemical manufacturing and often prepared by the reduction of phosphoric acid. This article will look into the different properties of this compound, such as its uses, side effects, and dosage information.

What is dipotassium phosphate in food?

Dipotassium phosphate is a salt that occurs naturally in plants, animals, and humans. It is also known by the names dipotassium hydrogen phosphate and dipotassium dihydrogen phosphate. It is commonly used as a food additive and as an emulsifier.

Dipotassium phosphate can be found in many foods including baked goods, crackers, potato chips, and other snacks. It is also used in products like ice cream, margarine, processed cheese spreads, and other types of cheeses.

The Food and Drug Administration (FDA) has approved dipotassium phosphate as an indirect food additive for use in baking powder to help maintain leavening power and as a preservative for certain processed fish products.

What is dipotassium phosphate used for?

Dipotassium phosphate is an inorganic compound with the chemical formula KHPO4 or K2HPO4. It is an important fertilizer and a common ingredient in laundry detergents, soaps, and toothpaste.

Dipotassium phosphate has many uses in industry. It is used to reduce the pH of water during wastewater treatment, neutralize acids during mineral processing, and remove chlorine from water for drinking purposes. It can also be used in ceramics production as well as in water treatment processes such as distillation and reverse osmosis.

Dipotassium phosphate is used as a supplement in the treatment of hypophosphatemia, a condition that occurs when the body does not have enough phosphate in the blood. The most common cause of hypophosphatemia is chronic kidney disease (CKD), which causes the body to lose phosphorus through urine.

Dipotassium phosphate can also be used to treat calcium deficiency.

Dipotassium phosphate may also be used for purposes not listed in this medication guide.

How is dipotassium phosphate made?

The main process used to produce this chemical is the reaction between phosphoric acid and potassium carbonate. This reaction produces dipotassium phosphate and water.

The reaction is carried out in the presence of a catalyst such as cobalt or iron oxide, which speeds up the reaction by lowering the activation energy required for the reaction to take place. The catalyst also allows more of the reactants to come into contact with each other, which increases the rate at which they react with each other. The amount of catalyst used depends on how much dipotassium phosphate is needed: if only a small amount is needed then less catalyst will be used than if a lot is needed.

Dipotassium Phosphate is made from the reaction of sodium phosphate and potassium carbonate, with sodium hydroxide being used as a catalyst:

  • 3 NaHCO3 + 2 K2CO3 + H2O → 3 NaH2PO4 + 2 KCO3


Other names Dipotassium monophosphate; Secondary potassium phosphate; Dipotassium orthophosphate
Chemical formula K2HPO4
Molecular weight 174.18
CAS number 7778-77-0
Appearance White hygroscopic granular or powder
Solubility Freely soluble in water, insoluble in ethanol
PH 8.7 to 9.4 (1% solution)


dipotassium phosphate structure

As a weak base, DKP dissociates PO43- and H+ when dissolved in water. In addition, it reacts with water to form H2PO4- and OH- as indicated by the following chemical equation:

  • HPO42- → PO43- + H+
  • H2PO4- + H2O → H3PO4 + OH-

What is the application of dipotassium phosphate?

There are many applications for DKP, including food additives, fertilizers, and many other uses.


In food, dipotassium phosphate is commonly used as a buffer, mineral supplement, sequestrant, emulsifier, and synergistic antioxidation agent. As a base, it cannot be used as a leavening agent like monopotassium phosphate.

The following food products contain this ingredient:

  • Non-dairy creamers
  • Milk products
  • Mineral supplements
  • Powdered beverages
  • Cheeses
  • Meat
  • Low-sodium products

Buffering agent

As a buffering agent or acidity regulator, DKP maintains a specific pH for solutions. When acids or bases are added to a solution, DKP reduces a rapid change in pH.

In non-dairy creamer, DKP is used to prevent coagulation. It prevents precipitation in milk by increasing pH and ensuring milk protein stability.


A common source of phosphorus and potassium is DKP. Coca-Cola’s beverages contain potassium, which provides nutrition and regulates blood pressure.( 2)


In bodybuilding, weightlifting, and athletic performance, phosphorus plays an important role in the production of ATP (adenosine triphosphate). After sweating a lot, potassium replenishes our body with electrolytes.

It can be used as a source of phosphorus and potassium as well as a buffering agent in energy drinks.


In agricultural applications, as a water-soluble phosphorus and potassium fertilizer.


As phosphorus is an essential compound for the growth of microorganisms, DKP can also be used in the culture of microorganisms (e.g. fermentation processes of antibiotics and yeast).

Is dipotassium phosphate safe?

Dipotassium Phosphate is a common ingredient in many processed foods. It’s a salt, and it’s added to foods for the same reasons salt is added: It enhances flavor, helps preserve food, and keeps it from spoiling. It does not contain phosphorus, so it is safe for people with kidney disease or other conditions that require a low-phosphorus diet.

Dipotassium phosphate is used as an emulsifier in some processed foods. It prevents fats from separating from water and forming a layer on top of the product. The Food and Drug Administration requires that all ingredients in food products be listed on their labels. If you spot dipotassium phosphate on the label of a food product, you can count on it being safe to eat.

When used as a food additive, DKP is safe and almost without side effects. The FDA generally considers it safe (GRAS) when used as a sequestrant in accordance with good manufacturing practices. ( 3)

EFSA has also re-evaluated its safety and in 2019 established an ADI (expressed as phosphorus) of 40 mg/kg body weight (BW) per day.

Since 1982, JECFA has approved it as an acidity regulator, sequestrant, and yeast food.( 4)

Sodium phosphate is a chemical compound that contains sodium and phosphate, which is a mineral needed for the body to grow and function properly.

A lot of foods contain some amount of sodium phosphate, including milk, cheese and yogurt. It’s also found in packaged foods such as ketchup and other condiments.

The kidneys help remove excess sodium from the body through urine, but if you eat too much sodium phosphate, it can lead to kidney disease or other health problems.

High amounts of sodium phosphate in your blood can lead to high blood pressure (hypertension), which can increase your risk of heart disease and stroke. High blood pressure may not cause any symptoms until it leads to serious complications such as heart failure or kidney disease.

Dipotassium Phosphate is an ingredient that helps to create a thick consistency by increasing the viscosity of liquids. This means that when you add it to water, it will make the liquid thicker so that when you stir it around, there won’t be any lumps left behind.

Dipotassium phosphate also helps stabilize what would otherwise be unstable emulsions, allowing them to remain stable even at higher temperatures. This makes it useful for foods like salad dressings or sauces where oil and vinegar may separate from each other if they were not stabilized with an emulsifier like dipotassium phosphate.

Dipotassium phosphate works by coating small particles of food with a thin film called an adsorption layer which prevents them from coming together in larger clumps inside the mouth. This is why if you add it to smoothies or shakes they will taste smoother but less creamy than without it.

Is dipotassium phosphate bad for you?

Dipotassium Phosphate is not bad for you at all! It is actually quite beneficial. The only problem with it is that it can cause diarrhea if too much is consumed. Diarrhea will go away once the body gets rid of all of the dipotassium phosphates that were consumed. You may see some other side effects such as nausea or stomach cramps but these side effects are only temporary and should go away within a few hours after ingesting too much of this substance.

Dipotassium phosphate is used in foods to help prevent food from turning brown. It is also used in toothpaste to make teeth brighter by removing stains and plaque build-up on the teeth. Dipotassium phosphate has also been used topically on wounds as a healing agent because it helps stop bleeding from wounds very quickly, which speeds up healing time!

What are the dipotassium phosphate side effects?

Dipotassium Phosphate is a medication used to treat hypokalemia or low potassium levels. It belongs to a group of drugs called phosphorus supplements. This medication is available in generic form.

Side effects from dipotassium phosphate may include:

  • Heartburn or stomach pain
  • Nausea and vomiting
  • Diarrhea
  • Vomiting
  • Dizziness
  • Constipation

Where to buy dipotassium phosphate?

The best way to buy Dipotassium Phosphate is to buy it online. You can find the best deals on this product at the following places:

Amazon – This is one of the most popular online stores in the world and they sell almost everything that you could think of. They have an amazing selection of products and their prices are very competitive.

Walmart – Walmart is one of the biggest retailers in the world so you know that they have a large selection of products. Their prices are very competitive and they also offer free shipping on most items.

Grade Chemical – Grade Chemical is one reliable food additive in China. they can supply you with good price dipotassium phosphate.

Frequently Asked Questions

Disodium phosphate is a sodium-based salt. It’s synthesized by reacting phosphoric acid with sodium hydroxide, and it’s found naturally in many foods. The term “natural” is not legally defined, but generally refers to the fact that something is obtained directly from nature. While disodium phosphate can be created in a lab, it has also been found in nature since the beginning of time.

Disodium phosphate is not toxic to humans if ingested, but it may cause some mild side effects when taken in large doses. The most common complaints are diarrhea and nausea. If you experience any of these symptoms, call your doctor to find out if you need treatment.

Dipotassium Phosphate is not a preservative. It is a salt of potassium and phosphorus and has been used as an additive to food since the 1960s.

Dipotassium Phosphate is a vegan-friendly food additive that is used to improve the texture and consistency of a product. It’s also used as a preservative and a nutrient source.

It is considered safe for human consumption by the FDA, but it can be harmful to animals. The main ingredient in this food additive is potassium phosphate, which makes it suitable for those who follow a vegan diet.

No, dipotassium phosphate is not an acid. Acids have a pH of less than 7 on a scale of 0-14. While dipotassium phosphate has a pH of 6.3, this number is still too high to qualify it as an acid.

What is another name for dipotassium phosphate?

Dipotassium phosphate is also known as potassium dihydrogen phosphate, potassium hydrogen phosphate, and K2HPO4.

Disodium phosphate is added to foods for several reasons. First, it’s used as a preservative. Second, it can help keep food from turning dark or brown. Third, it can help prevent food from spoiling. Finally, disodium phosphate can help increase the shelf life of food products.


The above are just a few of the uses of Dipotassium Phosphate. It is used in various industries like food, construction, and the detergent industry. There are very few side effects that can be experienced from the above substances if taken in minimal amounts.

Potassium phosphate is a safe substance. If you have excess sodium in your body, then to lower the supra renal pressure and for protection of kidneys then you can use di potassium phosphate as it helps in reducing the sodium content in the body.

If you have any questions about Dipotassium Phosphate? Let us know in the below comments.

Sophie Feng

Sophie Feng

Sophie Feng is the author of gradechemical.com, she is the co-founder of the grade chemical network. She has been in grade chemical company since 2017, with a working knowledge of food chemical .

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