What is Sodium Diacetate (E262ii)? Uses, Safe, Side Effects

What is Sodium Diacetate (E262ii)? Uses, Safe, Side Effects


Table of Contents

Sodium diacetate, also known as E262ii and acetic acid sodium salt is a food additive that has many commercial uses. Despite its name, this additive does not contain any form of acetate. Rather, it is used to inhibit the growth of yeasts and mould in foods that undergo pasteurization by addition to the growth medium.

What is Sodium Diacetate (E262ii)? This article helps you understand what the chemical is and what it tastes like. It also covers its uses and explains how it is made.

What is Sodium Diacetate?




Sodium diacetate is a chemical compound with the formula NaC4H4O4. It is a salt of acetic acid and sodium hydroxide, soluble in water. Sodium acetate is used to make other chemicals, as well as substances like soap and glass, and has been found in meteorites.

Sodium diacetate was discovered by French chemist Henri Victor Regnault in 1847. It was first prepared by heating acetic acid with sodium hydroxide at 100 °C under pressure. The major industrial route today involves heating sodium acetate with acetic anhydride at 200–300 °C:

The resulting mixture is distilled under a vacuum to give the product a white solid in 80% yield. It can also be produced by passing carbon dioxide through an aqueous solution of caustic soda containing dissolved acetate salts, followed by evaporation of the liquid phase to give a crystalline mass which is filtered off and dried.

What is sodium diacetate used for in food?


Sodium diacetate is a preservative that prevents the growth of molds and yeasts in food. It’s often used with other preservatives, such as sodium erythorbate and sodium nitrite, to inhibit bacterial growth.

Sodium diacetate can be found in many types of food products, including:

Baked goods


Canned meat and vegetables

what does sodium diacetate do to your body

What’s sodium diacetate used for?


Sodium diacetate is an organic compound that is a white solid. It is also known as sodium bisulfite, sodium acid pyrophosphate, and disodium hydrogen pyrophosphate.

Sodium diacetate is used to preserve foods and as an antiseptic agent. It is also used in the production of drugs and other chemicals, in the textile industry, for bleaching hair, and as a deodorant.

Sodium diacetate is used to preserve foods by inhibiting the growth of bacteria and mold. It can be used in combination with other preservatives such as sorbates or benzoates to inhibit yeast growth. It may be used alone or in combination with other preservatives such as sorbates or benzoates to inhibit yeast growth.

Sodium diacetate can be used as an antiseptic agent for cleaning wounds and skin abrasions, but it may cause swelling if it comes into contact with broken skin so it should not be applied directly to unbroken skin.

Sodium diacetate is used as an acidity regulator and flavor enhancer in cheese products, canned fruits, vegetable products, pickles, and sauces; as a preservative in dried fruit and nut products; and as an ingredient in pet foods.

What is sodium diacetate made?


Sodium diacetate is a chemical compound with the formula NaC2H3O2. It is the sodium salt of acetic acid and is also known as pyrosulfuric acid (PDC).

The pure substance is colorless. It forms crystals that are highly soluble in water, alcohols, ethers, esters, and chloroform. Sodium diacetate is produced from acetic acid by the following reaction:


How is sodium diacetate made?


Authorities, such as the FDA and EFSA, generally mention two manufacturing processes.

As per FDA 21CFR184.1754, its technical grade is produced by reacting sodium carbonate with acetic acid or by reacting anhydrous sodium acetate with acetic acid.

As per the information provided by EFSA, sodium hydroxide reacts with glacial acetic acid to produce sodium acetate, leaving sufficient free acid after the reaction.


Other names Sodium hydrogen diacetate
CAS number 126-96-5
Chemical formula NaH(C2H3O2)2 (anhydrous) Or C4H7NaO4·nH2O (n = 0 or 3)
Molecular weight 142.09 (anhydrous)
Solubility It is freely soluble in water. Dissociates into acetate, sodium, and hydrogen ions.
PH One in ten solutions have a PH value between 4.5 and 5.0.
PKa 4.75



White crystalline powder




What is the application of sodium diacetate?

As a result of its antimicrobial properties, vinegar taste, and PH regulation, it can be used in food, feed, cosmetics, and pharmaceutical products.


Generally, it is used in bakery products, meat products, and savory products. In addition, it is easy to use and transport, as liquid acetic acid must be transported in a liquid form.


Preservatives such as this are used in bread dough to extend shelf life. Additionally, it exhibits synergistic antimicrobial properties with calcium propionate.


A low level of sodium diacetate (e.g., less than 0.2%) can lower the pH of meat products, inhibiting the growth of molds and bacteria, such as Listeria monocytogenes.

The reason for this is not only its pH-lowering effects but also the inhibition of listerial growth by the acetate ion.

In combination with sodium diacetate, sodium lactate or potassium lactate retards microbial growth more effectively.

Savory products

Due to its high concentration of acetic acid (39-41%), In addition to being a dry vinegar, it serves as a flavoring agent. The ingredient is commonly used in savory products such as cookies, chips, condiments, sauces, soups, potato crisps, and salads.

Acidity adjustment

In food, it acts as a buffering agent. Liquid or dry, it can be applied easily.

Feed additive

Preservatives such as sodium diacetate can be used in poultry, pig, and pet feed.


According to the “European Commission database for information on cosmetic substances and ingredients”, it can act as a buffering and masking agent.


In dialysis solutions, sodium diacetate controls the pH level. Clinics also benefit from storing dry mixes rather than liquid products, since only a liquid product needs to be dissolved.

Is sodium diacetate safe to eat for the body?

Sodium diacetate is considered safe for human consumption by the FDA (Food and Drug Administration) and other governmental agencies around the world. It has no known side effects when consumed in small amounts by humans or animals over short periods of time (less than one year). There have been no reports of any significant side effects in humans who consume this preservative regularly over long periods of time either


At levels not exceeding current good manufacturing practice, it can be used as an antimicrobial agent, flavoring agent, adjuvant, and pH control agent in food.

Here is a list of approved foods and their maximum usage:

  • Baked goods: 0.4%
  • Gravies and sauces: 0.25%
  • Fats and oils: 0.1%
  • Meat products: 0.1%
  • Soft candy: 0.1%
  • Foods for snacking, soups, and soup mixes: 0.05%


The European Union (EU) has approved sodium diacetate (E262(ii)) as a food additive in accordance with Annex II and Annex III to Regulation (EC) No 1333/2008 on food additives.


A list of its approved applications appears separately under E262(ii) or in Group I where quantum satis is used.

Foods that may contain it include:

  • Fruits and vegetables in cans or bottles
  • The bread
  • Pain courant français; Friss and apples, they’ve been on the market a while
  • Foods based on cereals and baby foods (adjusted pH)

UK Food Standards Agency

This item is categorized as Others.

Food Standards Australia New Zealand

Australia and New Zealand have approved it with code 262 as an ingredient.


Function Class: food additives, sequestrants, preservatives,

A safe daily intake, defined as “0-15 mg/kg bw,” has been set since 1973.

Is sodium diacetate bad for you?

Sodium diacetate is used in medical and cosmetic treatments as a desiccant. This means that it’s used to dry out wounds, cuts, and burns. It’s also found in many cosmetics because it has a low level of toxicity and it won’t irritate the skin.

It’s important to note that sodium diacetate isn’t typically used as an active ingredient in these products, but rather as an inactive ingredient meant to help preserve other ingredients. The problem with this is that there are no long-term studies on the effects of sodium diacetate on humans or animals. As such, it’s difficult to say whether or not it could cause negative health effects over time or if there are any dangers associated with using products containing this ingredient.

There are some reports that suggest that sodium diacetate can be harmful when ingested or inhaled in large amounts over time, but these reports aren’t backed up by scientific evidence and haven’t been proven by researchers who specialize in these areas of study.

What are the Possible side effects of sodium diacetate?

Some consumers wonder if sodium diacetate is harmful to their health and what its side effects are. There are concerns among consumers regarding synthetic preservatives in their foods. There are few reports regarding sodium diacetate’s risk. The product may cause allergic reactions in some people.

The following side effects have been reported in people who have taken sodium diacetate. However, it is not clear if they were caused by sodium diacetate or by something else:

Allergic reactions (hypersensitivity). These may include skin rash and itching, rashes, swelling of the face, lips, tongue and throat (angioedema), asthma attacks, dizziness and blurred vision.

Diarrhoea. Diarrhoea may be caused by the bacteria that live in your gut when you take antibiotics. These bacteria can cause diarrhoea when they die off. Diarrhoea is often mild and short-lived but it can be treated with a simple remedy such as taking more fluids or eating less fibre in your diet.

Vomiting. Vomiting is also common in people who have taken antibiotics and usually goes away on its own within a few days. It can be treated by drinking lots of liquids to prevent dehydration (losing too much fluid).

Nausea or vomiting (feeling sick). These are common side effects of antibiotics and usually go away within a few days without treatment. They are often caused by changes in the balance of bacteria living in your gut after taking antibiotics, which can make you feel nauseous

Where to buy sodium erythorbate?

If you’re looking for a good source of sodium erythorbate, then you might want to consider buying it in bulk. This is a great option if you have a large family or if you plan on using it in large quantities. You can purchase sodium erythorbate online from many different companies. Here are some examples:

Amazon: Amazon carries several brands of sodium erythorbate at discounted prices. The product ships directly from Amazon and will arrive at your home within days of ordering it online.

Walmart: Walmart sells several different brands of sodium erythorbate in liquid form or powdered form at discounted prices compared to other retailers such as Sam’s Club or Costco that sell similar products at higher prices than Walmart offers them for online through its website.

Grade Chemical: Grade Chemical is one reliable sodium erythorbate manufacturer in China. if you purchase in a large quantity, it is good decision purchase from them. the price is much more competitive than local store.

Frequently asked questions

Sodium diacetate is a food additive that is used to preserve food, according to the FDA. It can be found in cheese and meat products, as well as soft drinks.

Sodium diacetate is a flavor enhancer, which means it makes food taste better. It’s found in many foods, including:



-Cured meats (bologna, salami)

-Smoked meats (hot dogs, jerky)

Sodium diacetate vs Sodium acetate

Sodium diacetate and sodium acetate are two chemical compounds that are both used as food preservatives. They are both derived from acetic acid, but they differ in the way they react with water.

Sodium diacetate reacts to produce acetic acid and sodium chloride, while sodium acetate reacts to produce acetic acid and sodium bicarbonate.

Both of these compounds have a wide range of applications in food production, from preventing bacterial growth to preserving flavor and texture.

Sodium diacetate is also known as acetic acid salt. It is a white crystalline solid with formula NaCHCO2Na and molar mass of 74.12 g/mol. Its melting point is 6 ˚C and boiling point is 300-302 K (25 ˚C).

Sodium acetate, also known as sodium ethanoate, is a sodium salt of acetic acid. It is a white crystalline solid with formula NaCHCO2Na and molar mass of 74.12 g/mol. Its melting point is 6 ˚C and boiling point is 300-302 K (25 ˚C).

Is sodium diacetate natural?

Yes, sodium diacetate is natural. It can be found in many fruits, such as apples and pears, as well as in cheese.

Is sodium diacetate halal?

Yes, Sodium diacetate is halal because it does not contain any ingredients derived from pork or alcohol, which are forbidden in Islam.

Is sodium diacetate kosher?

Yes, sodium diacetate is kosher. Sodium diacetate is a salt and therefore does not contain any meat or dairy products, which are forbidden for kosher preparation.

Is sodium diacetate gluten free?

Yes, sodium diacetate is gluten free. Sodium diacetate is a salt of acetic acid and sodium hydroxide. It is used as a flavoring agent and preservative in the food industry.

Is sodium diacetate vegan?

Yes, sodium diacetate is vegan. Sodium diacetate is an organic compound that occurs naturally in fruits and vegetables. It can also be made synthetically. The FDA considers it a food additive, and it’s used for a variety of purposes, including as an antioxidant and preservative in foods and beverages, as well as in personal care products such as shampoo.

Does sodium diacetate contain milk?

Sodium diacetate does contain milk. We use it to prevent the growth of yeast and molds in our products, which means it is used as an anti-fungal agent. It’s also used as a preservative in other products like jellies and meat products.

Sodium Acetate VS Sodium Diacetate

Sodium acetate and sodium diacetate are two different types of salts that have very similar chemical formulas. Both compounds consist of one sodium ion and two acetate ions. The difference between the two lies in their atomic structures.

Sodium diacetate has a linear structure, while sodium acetate has a cyclic structure. This means that the atoms in sodium diacetate are arranged in a straight line, while those in sodium acetate form a ring with alternating single and double bonds.


Overall, the use of sodium diacetate in food production is considered safe in current recommended-use levels. In order to promote safe use of sodium diacetate by consumers, consumers should be fully informed of the amounts that make up an ADI and the appropriate level of usage.

The ultimate purpose of sodium diacetate is to extend shelf life in food products. It is mainly used with dairy and meat products, but it is also getting more popularity in non-meat type of foods. It seems that the use of this product is not going to subside so soon.

If you have any comments about sodium diacetate? Let use know in the below comments.

Sophie Feng

Sophie Feng

Sophie Feng is the author of gradechemical.com, she is the co-founder of the grade chemical network. She has been in grade chemical company since 2017, with a working knowledge of food chemical .

Recent Post:

Leave a Comment

Your email address will not be published. Required fields are marked *


One professional food chemical manufacturing company in China, we can supply different types of food additives, flavors fragrances, feed additives, food ingredients, and custom chemicals, etc

Fill out the form and our sales team will contact you with our best prices.

Scroll to Top

Ask for Quick Quote

We will contact you within 1 working day, please pay attention to the email.